Dr. D. Y. Patil School of Science and Technology
Tathawade, Pune- 411033.

The Role of Explainable AI in Healthcare

The Role of Explainable AI in Healthcare

Discover how Explainable AI is improving patient safety, trust, and diagnostics in healthcare through transparent, actionable insights.

Ms. Priyanka Pawar
April, 30 2025
18

Artificial Intelligence (AI) is transforming healthcare—enhancing diagnostics, predicting patient risks, optimizing workflows, and personalizing treatment. But as these systems grow more complex, one question becomes critical: Can we trust AI if we don’t understand how it works?

This is where Explainable AI (XAI) comes in.

Unlike traditional "black-box" models that offer predictions without context, explainable AI aims to make the decision-making process transparent. In a field like healthcare—where decisions directly impact human lives—this transparency isn’t optional; it’s essential.

Why Explainability Matters

1. Enhancing Patient Safety

AI systems, while powerful, are not infallible. If a predictive model makes a mistake, explainability helps identify what went wrong—whether it’s flawed data, a misinterpreted pattern, or a biased assumption. Understanding these reasons can prevent future errors and improve overall safety.

2. Building Clinician Trust

Doctors are trained to reason and validate diagnoses. An AI system that simply states, “This patient is at high risk of heart failure,” won’t gain much traction unless it explains why—whether it’s due to abnormal vitals, prior medical history, or medication patterns. When clinicians understand an AI's reasoning, they’re more likely to integrate it into their practice.

3. Regulatory and Ethical Compliance

Healthcare AI is subject to strict regulatory standards. Agencies like the FDA are increasingly requiring transparency in algorithmic decision-making, especially for high-risk applications. Explainable AI is a key component in meeting these evolving standards.

4. Detecting and Reducing Bias

Medical data can carry the imprints of systemic bias. AI might inadvertently make decisions influenced by race, gender, or socioeconomic factors. Explainable models can reveal when such variables are improperly weighted, allowing developers and clinicians to intervene.

How Explainability Is Achieved

  • Interpretable Models: Some models, like decision trees or logistic regression, are inherently more transparent. While they may be less complex than neural networks, their clarity is often more valuable in clinical settings.
  • Visual Aids in Imaging: In radiology, AI models now often include heatmaps or annotated images showing areas of concern, offering radiologists visual explanations to support diagnoses.

Real-World Impact

AI models have revolutionized various sectors, including ICU monitoring, mental health monitoring, radiology, and medical imaging. In ICUs, explainable AI models can detect early signs of sepsis, a life-threatening infection, by highlighting contributing factors. This transparency helps clinicians validate the alert, enable quicker interventions, and reduce alarm fatigue. Mental health apps provide visual timelines, summaries, and daily insights to help patients and therapists better tailor treatment plans. In radiology, explainable AI has introduced visual explanation techniques, like saliency maps or heatmaps, to highlight regions in an image that influenced the AI's prediction. These visual aids help radiologists validate or contest AI findings, understand false positives or negatives, and use AI as a "second opinion" without losing clinical control. This collaborative workflow increases diagnostic accuracy and confidence, especially in busy or resource-constrained environments.

Conclusion

Explainable AI is revolutionizing healthcare by providing accurate, understandable, and actionable AI-driven decisions. It enhances human expertise, enabling clinicians to make confident decisions. This transparency mitigates bias, improves patient trust, and ensures regulatory compliance. As AI evolves, it will shape a healthcare landscape where both AI and clinicians work together to provide safer, more effective care. As AI evolves, it will continue to shape the future of healthcare.

The Dr. D. Y. Patil School of Science and Technology, Tathawade campus, Pune, organizes workshops, seminars, and expert sessions on recent trends in technology.

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